Consistent with Class v. United States, 583 U.S. _, 138 S.Ct. 798 (2018), are as-applied constitutional challenges to statutes of conviction waived by an unconditional guilty plea, and is the standard of review de novo or plain-error?

Consistent with District of Colombia v. Heller, 554 U.S. 570 (2008), and United States v. Lopez, 514 U.S. 549 (1995), does Congress have authority to federally criminalize a wholly intrastate firearm sale and possession based only on the minimal showing that the firearms, at some point in time, traveled in interstate commerce?

Whether as-applied constitutional challenges to statutes of conviction are waived by an unconditional guilty plea, and the standard of review